Abcs Of Probiotics For IBS

By Patty Goff


Probiotics are live microorganisms added to food to remain active in the intestine and exert important physiological effects. Ingested in sufficient quantities, can have beneficial effects, such as contributing to the balance of the intestinal microbiota of a host and enhance the immune system. Probiotics for IBS can pass through the digestive tract and feces recovered alive, but also adhere to the intestinal mucosa. They are not pathogenic, except in cases where immunocompromised individuals are supplied.

It does not document the benefit to any other strain, although the same species as the one tested, nor a fortiori for the entire group of probacteria. The FAO / WHO which provides this definition refers to non-pathogenic microorganisms present in food or added to them. This distinction is often not taken into consideration, is of extreme importance as regards the safety of use of viable bacteria.

The consequences of these interactions as a whole, however, are yet to understand. It is believed that probiotics can have several beneficial effects on immune function. They can protect from the pathogenic species through inhibition of growth through competition and, as suggested by some evidence, act on the immune system by increasing the number of cells that produce immunoglobulin, enhancing phagocytosis, increasing the proportion of T lymphocytes and NK cells (Natural Killer).

But the two enzymes present in such products do not play a beneficial role in human organisms because they die as soon as they come into contact with the gastric juices. According to FAO / WHO guidelines, good bacteria are defined only those microorganisms that can demonstrate, when ingested in adequate amounts, exert beneficial functions in body.

It is still not clear how probiotics may counteract the overreaction of the immune system, but a potential mechanism seems to be the desensitization of T lymphocytes, an important component of the immune system, to pro-inflammatory stimuli. An interesting beneficial effect of some probiotic strains in this regard relates to atopic dermatitis and asthma in children; However, there are conflicting data in the literature. It does not seem that pro biotics can reduce the effects of persistent eczema and dermatitis.

Nobel laureate Eli Metchnikoff, who worked at the Pasteur Institute in the early years of the twentieth century, hypothesized that these effects arising from an improvement in intestinal microbial balance through inhibition of pathogenic bacteria. Since then, knowledge about biotics have been enriched by scientific and clinical studies in large numbers and with great frequency.

These results can be considered valid also for all those who have similar symptoms but do not have a diagnosis of IBS. Some strains gave positive results for this type of activity, including the reduction of constipation and restoring a "normal" transit time. Interesting are the data obtained in a 2009 study on the efficacy of Lactobacillus GG in the outpatient management approaches with natural disturbances related to formar diarea-predominant irritable bowel syndrome and bloating.

A probiotic microorganism can you say if it meets the following requirements: is safe for use in humans: a useful reference in this sense can be a list of bacterial species presumptively classified as safe by EFSA (QPS). In any case, the probiotic micro-organisms should not be carriers of antibiotic-resistance acquired and / or transmissible. It should be active and vital in the intestine in sufficient quantity to justify the possible beneficial effects observed in studies of effectiveness. Be able to persist and multiply in human gut. Be able to confer a physiological benefit demonstrated according to the criteria reported in FAO or WHO documents on evaluation of pro-biotics for food use.




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